Cost-Minimization Analysis of Metformin and Acarbose in Treatment of Type 2 Diabetes

نویسندگان

  • Shuyan Gu
  • Lizheng Shi
  • Monika Sawhney
  • Huimei Hu
  • Hengjin Dong
چکیده

Background: Metformin is the first-line oral hypoglycemic agent for type 2 diabetes mellitus (T2DM) per international guidelines with proven efficacy, safety, and cost-effectiveness. However, little information comparing it with acarbose exists. Objective: To study the costeffectiveness of metformin and acarbose—two extensively adopted agents—in treating T2DM. Methods: Cost-minimization analysis was conducted on the assumption that metformin and acarbose have equivalent clinical effectiveness. The cost of treatment was detected and evaluated from a payer’s perspective. In sensitivity analyses, several clinical scenarios were developed according to clinical practices and physicians’ prescribing behaviors in China. Results: Metformin can save annual treatment costs by 39.87% to 40.97% compared with acarbose. ee front matter Copyright & 2015, International S

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تاریخ انتشار 2015